Gehaltsübersicht für Biology in Schweiz

Post-doctoral position in cilia biology 100 %Department of Molecular Life Sciences Post-doctoral position in cilia biology100 % Primary cilia are key cellular organelles involved in transduction of a variety of signals that influence cell behavior during development and cell homeostasis. Their dysfunction is associated with a group of human disorders collectively termed “ciliopathies”, that can affect most organ systems, with predominant retinal, renal and CNS involvement. Our research group «ciliopathies» focuses on understanding the role of this organelle during development and disease pathomechanisms using a combination of human genetic studies, zebrafish animal and human iPSC-derived models. The group is based at the Department of Molecular Life Sciences of the University of Zurich and interacts closely with groups within the department, the university and internationally. Your responsibilities The successful candidate will study the consequences of ciliary gene dysfunction in iPSC-derived models for ciliopathies. Currently established models in the lab include renal and neuronal models. We are particularly interested in studying the ciliary protein content in these various cell types to investigate the tissue-specificity of this organelle. We routinely apply CRISPR genome editing, transgenesis techniques with live imaging as well as genomic experiments (RNA-sequencing, proteomic analysis). Your profile This position is ideal for advanced post-doctoral fellows who aim to establish their career using iPSC-derived models. Applicants should hold a good PhD degree in a relevant discipline (e.g. molecular biology, cell biology, development, etc) and have published work using human cell culture methods. Ideally, they should have acquired previous post-doctoral experience and feel ready to independently lead not only their own project but also other group members (PhD and master students). Experience with iPSCs and derived models is a pre-requisite for this position. Experience in genome engineering using CRISPR/Cas9 would be advantageous. Coding skills for enhancing existing data analysis pipelines in the lab and experience with -omics experiments would be an appreciated plus. The candidate should have an interest in developing novel approaches to explore the molecular basis underlying ciliopathies. An ability to work independently allied with a strong team spirit, scientific creativity, and high motivation are expected. What we offer The University of Zurich offers optimal working conditions in a rich scientific environment with a large and active community and excellent core imaging and genomics facilities. The group has a functional stem cell laboratory and the successful candidate will collaborate closely with members from other groups studying hiPSC-derived models for different projects. This position is available immediately and is funded for up to three years (yearly rolling renewal). Acquisition of additional personal funding will be supported and highly encouraged. Place of work Winterthurerstrasse 190, Zürich, Switzerland Start of employment immediately or upon agreement

PhD Position in Cell Biology Berne 100 % Inselspital, Universitätsspital Medical division cross-sectional service provider University Institute of Diagnostic and Interventional Neuroradiology per 01.03.2024 or upon agreement Limited to 3 years Temporary Inselspital, Universitätsspital Bern Freiburgstrasse, CH-3010 Bern Schweiz What you can expect We are offering an exclusive PhD position to a talented and highly motivated student. You should be interested in investigating interactions between metallo-drugs and cells using a broad variety of biochemical and cell biological methods. In addition, the applicant has the unique opportunity to work interdisciplinary in close collaboration with numerous research groups located at the University of Bern and Inselspital Bern. Your Profile We are looking for an enthusiastic student with a master's degree in cell biology / biology / chemistry / biochemistry / biomedicine / pharmacy. For this position, you should be detail-oriented, and enjoy multifaceted scientific challenges. While competence in molecular biology, tissue culture, and related domains is certainly advantageous, it is not an obligatory prerequisite. What we offer We provide you with the benefits of a university hospital employee including a state-of-the-art research environment. The position is open from March 2024 and will be funded for a period of three years. The PhD position is full time and paid according to the Swiss National Science Foundation. First rate training and further education Our university clinics and institutes are \"A\" grade training organisations Support with individual professional progression and career paths Competent onboarding weiterbildung Research partnerships In partnership with the University of Bern, we offer the opportunity to participate in national and international research networks forschungskooperationen Equal opportunities and diversity We promote a corporate culture which recognises the value of diversity as an asset We are committed to ensuring equality between men and women We do not tolerate discrimination in any form chancengleichheit Questions about the job? For further information please contact Dr. Nico O. Ruprecht Scientific Assistant +41 31 632 49 23 INSELSPITAL3010 Berne

The Position In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed. 360 Labs Initiative at a Glance The 360 Labs are a new capability that is currently being built up within the Pharmaceutical Research and Early Development organization (pRED). The primary mission of this effort is to provide greater access and support for the use of cutting-edge biomedical research technologies by scientists across our discovery portfolio. Operating as an integrated ecosystem, the 360 Lab environment will deliver core scientific technologies, expertise and enabling activities, as well as facilitate knowledge sharing and learning experiences in close collaboration with our therapeutic areas and functions. Together, these efforts will serve to increase the speed, enhance the robustness and improve the sustainability of our exploratory research and early discovery activities. We are currently recruiting scientific professionals with varied backgrounds in Flow Cytometry, Genomics, Proteomics, Histopathology and Microscopy / Imaging. In these new roles, your collaborative mindset is as valued as your scientific expertise. The 360 Labs are by nature a hands-on, interactive workplace where face to face presence in our labs is a priority. Our ambition is to bring to life a thriving workplace environment, acting as an highly integrated ecosystem, supporting research and development, working collaboratively, and focused on fostering excellence and sustainability. Job Mission and Impact The 360 Labs Initiative is seeking a Matrix Leader for Spatial Biology. You will have a strong background in the development and application of spatial approaches (both genomics and imaging-based) to understand disease biology. You will operate as a part of a matrix team and will collaborate closely with the platform heads, lab scientists and data analysts from each of the 360 Labs technology platforms, as well as with experts from our therapeutic disease areas and functions to conceptualize and execute our spatial biology strategy to support discovery projects undertaken within the 360 Labs technology ecosystem. Your Role and Responsibilities Act as a strategic visionary, providing key guidance and oversight in the deployment and application of spatial biology approaches across the discovery research space in pRED. Serve as a key member of the 360 Labs leadership team, working closely with the Global Head, to develop a bold vision and strategy for spatial biology by close interaction with senior leaders and key stakeholders across pRED. Serve as a Matrix Leader collaborating across the 360 Labs technology ecosystem along with scientific experts from our therapeutic areas and functions to prioritize and implement innovative spatial biology strategies to enable the exploration of disease-relevant hypotheses. Work collaboratively to continually evolve our spatial biology strategy by innovating new approaches, staying up to date with the scientific literature, actively engaging with internal and external spatial biology communities, and continuously evaluating new technologies in the spatial biology space. Your Profile Required Proven track record of engagement with senior leaders and key stakeholders and leading cross-functional teams. A PhD degree in biology, chemistry, or a related field with 5 years professional experience in an academic setting and / or pharmaceutical industry / biotech sector. An experienced experimentalist with in-depth theoretical and hands-on knowledge in the development and application of genomics and imaging-based spatial biology assays to understand how cells organize and interact across complex tissue landscapes. Established track record of scientific accomplishments and successful collaborations documented via publications in high-impact scientific journals and presentations at international conferences. Familiarity with the bioinformatics tools and programming languages commonly used in the analyses and interpretation of spatial biology-related datasets. Strong awareness of the emerging trends and technology developments across the spatial biology space. In addition to your scientific expertise and critical technical skills we are looking for candidates who: are a strategic leader that can architect a compelling vision; serve as a coach to develop and mentor junior and senior team members; and act as a catalyst by leading by example; are curious, have a growth mindset, are resourceful and flexible in problem solving, have excellent organizational skills, can think outside the box, and have a demonstrated ability to implement new ideas in a fast-paced research environment; bring excellent written communication and presentations skills with a high fluency in English; have a keen interest in continuously building a personal network and who will thrive in a dynamic, inclusive environment which gives you full accountability for your own contributions and development; have an excellent understanding of the operations processes involved in early drug discovery & development. Your Location This position is based in Basel. Our commitment Roche commits to recognizing talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career. We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be. Who we are At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity. Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more. Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events. We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche. Roche is an Equal Opportunity Employer. We believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.Über das Unternehmen:1201 F. Hoffmann-La Roche AG

The Zampieri group offers a post-doctoral research opportunity in the context of systems pharmacology, computational biology and metabolic regulation. These positions will be based in the Department of Biomedicine ( ) in Basel, one of the world's leading locations for life sciences, home to several companies and institutions. The mission of the group is to understand fundamental mechanisms regulating short- and long-term metabolic adaptation to genetic and chemical perturbations to find new and unconventional therapeutic strategies, ranging from antibacterial to anticancer drugs. To this end, we develop new ways to combine state-of-the-art technologies in metabolomics with mathematical modeling.ProjectStudy how bacterial susceptibility to antibiotics depends on the metabolic and physiological states of bacteria. We are looking for a highly motivated Post-Doc researcher to study how bacterial susceptibility to antibiotics depends on the metabolic and physiological states of bacteria (60% wet lab and 40% computational).Your positionThe candidate will have the opportunity to exploit some of the cutting-edge experimental and computational methods, comprising constraint-based and kinetic modeling, statistical analysis of large datasets, high-throughput metabolomics, time-lapse microscopy, to investigate how to pharmacologically interfere with fundamental mechanisms in the regulation of bacterial metabolism. Available resources at the department include a mouse facility, high-end FACS, IT and microscopy facilities, the Life Sciences Training Facility (for gene expression and proteome profiling) and much more.Your main tasks will be:Apply and develop model-based and statistical approaches to analyze and interpret large compendia of metabolome profiling of small molecules effects on bacteria.Adapting existing and developing improved experimental protocols for the high-throughput metabolomics analysis of drug-perturbed bacteria across different growth conditions.Unravel the hidden potential of apparently inactive molecules in hampering bacterial infectionDetermining the underlying mechanisms that link antibacterial efficacy to the metabolic or physiological state of bacteria.Testing their relevance in host-like environmental conditionsSupport and preparation of scientific reports and journal articlesYour profileThe candidate is expected to have a strong background and interest in quantitative disciplines, excellent teamwork and communication skills in English. The candidate will have the opportunity to develop the following project with a lot of academic freedom and strong support from senior members in the lab, and at the same time to play an active role in shaping and in creating inspiring research and working environment. Essential:PhD in (Bio)Physics, (Bio)engineering, Biological Sciences, Microbiology, Biochemistry, Systems Biology, Molecular Biology, Bioinformatics/Computational Biology, or related fields.Experience in designing and running experiments with microbial cultures in the laboratoryExperience with programming language (e.g. Matlab, R or Python)Motivation to work in an international research environmentHighly desirable:Hands-on experience with key biochemical and molecular biological methodsExperience with and/or motivation to learn systems biology approaches, high-throughput methodologies.Good communication skillsInterest in mathematical modeling of metabolic and regulatory/signaling networkWe offer youIn line with our and Uni Basel values ( ), we are committed to sustain and promote an inclusive culture, ensure equal opportunities and value diversity and respect in our working and learning environment.You will have access to state-of-the-art research equipment in metabolomics, cell biology, time-lapse microscopy.You will work in a dynamic and highly interdisciplinary team including computer scientists, experimentalists and clinicians.You will be involved in cross-disciplinary collaborations and have training opportunities to further develop and grow your scientific interests.Access to a large consortium of experts in different disciplines, such chemistry, engineering, clinics, computational biology and (Micro- / Cell- / Immune-)Biology ( ).Opportunity to work in close contact with other basic- and clinical-research groups at the Department of Biomedicine and the Biozentrum in BaselSupport from highly competent, experienced team members and potential to lead projects with a high degree of academic freedom4000 BaselPost-Doc position in quantitative biology (Zampieri Lab)

Die AO ist eine medizinisch geleitete, gemeinnützige Organisation, ein globales Netzwerk von Chirurgen und die weltweit führende Ausbildungs-, Innovations- und Forschungsorganisation, die sich auf die chirurgische Behandlung von Traumata und Erkrankungen des Bewegungsapparates spezialisiert hat. Wir verfügen über ein globales Netzwerk von über 520'000 Fachleuten des Gesundheitswesens. Jedes Jahr bieten wir über 870 Fortbildungsveranstaltungen auf der ganzen Welt an, die von fast 8'000 Fakultätsmitgliedern unterstützt und von über 82'600 Teilnehmern besucht werden. Wir haben etwa 20'000 Chirurgen als Mitglieder, die in den Bereichen Trauma, Wirbelsäule, Kraniomaxillofazial, Veterinärmedizin und rekonstruktive Chirurgie arbeiten. Weitere Informationen können auf unserer Homepage aufgerufen werden: Die Aufgabe des AO Forschungsinstituts (ARI) besteht darin, Spitzenleistungen in der angewandten präklinischen Forschung und Entwicklung auf dem Gebiet der Traumata und Erkrankungen des Bewegungsapparats zu erbringen und dieses Wissen in eine effektivere Patientenversorgung weltweit zu übertragen. Das ARI leistet qualitativ hochwertige angewandte präklinische Forschung und Entwicklung, die auf klinische Anwendungen/Lösungen ausgerichtet ist, und erforscht und verbessert die Leistungsfähigkeit von chirurgischen Verfahren, Geräten und Substanzen. Es pflegt eine enge Beziehung zur medizinischen Gemeinschaft der AO, zu akademischen Gesellschaften und Universitäten und bietet ein Forschungsumfeld und Unterstützung für AO Kliniker.Anstellungsverhältnis: Permanent Diese Stelle befindet sich in: Davos Platz, CH Pensum: 100% Gewünschtes Erfahrungsniveau: Professional Newcomers Bewerbungsunterlagen werden in folgenden Sprachen entgegengenommen: Deutsch Ihre Aufgaben Mitverantwortung für den täglichen Betrieb des Biologie-Labors und der damit verbundenen organisatorischen Aufgaben sowie Wartung der Geräte (z. B. Zellkultur-Inkubatoren, Sicherheitswerkbänke, Pipettenkontrolle) Zusammenarbeit mit den Wissenschaftlern an Projekten mit Zell- und Gewebekulturen und biochemischen und molekularbiologischen Analysen Aktive Teilnahme an der Ausbildung von Lernenden, Studierenden und Stipendiaten Projektbezogene Dokumentationen und Hilfe bei der Bearbeitung von SOP Leitlinien Umsetzung und Gewährleistung der Sicherheitsbestimmungen im Laborbereich Ihre Kompetenzen Abgeschlossene Ausbildung zur Laborantin/ Laborant (EFZ Fachrichtung Biologie) oder gleichwertige Ausbildung Theoretische und praktische Erfahrung in der Säugerzellkultur Erfahrung mit 3D-Zellkulturen ist von Vorteil Erfahrung in der biochemischen und molekularbiologischen Analytik sind von Vorteil (z. B. spektralphotometrische Analysen, RT-PCR) Gute Englischkenntnisse (mündlich und schriftlich) sind vorausgesetzt Freude und Interesse an der Zusammenarbeit in einem internationalen Team Wir bietenEine interessante und abwechslungsreiche Tätigkeit in einem spannenden und innovativen Unternehmen Die Möglichkeit, Teil eines hoch engagierten internationalen Teams zu sein Moderne Infrastruktur Anforderungsgerechte Beschäftigungsbedingungen, die ein hohes Mass an Flexibilität in Bezug auf Arbeitszeiten bieten Wenn Sie die Anforderungen dieser anspruchsvollen Stelle erfüllen, reichen Sie bitte Ihre vollständige Online-Bewerbung (Motivationsschreiben, Lebenslauf, aktuelles Foto, Zeugnisse, Referenzschreiben usw.) über unser Online-Bewerbungssystem ein.Datum der Publikation: 29.12.2023 Ähnliche Stellen suchen: Copyright 2024 - AO Foundation, Clavadelerstrasse 8, 7270 Davos, Switzerland

 Website Die AO Foundation ist eine medizinisch ausgerichtete, unabhängige NonprofitOrganisation unter der Leitung von international renommierten Fachärzten für Traumatologie und Erkrankungen des Bewegungsapparates. Wir verfügen über ein globales Netzwerk mit über 385.000 MFaechrkräften desBewerbungsservices Bewerber-Cockpit anlegen  Bewerbungsvideoaufnehmen  Kandidatenprofil erstellenund von Firmen finden lassen  Bewerbungsfoto mit KI erstellen  Zum Bewerbungsratgeber16.11.2023 PhD Student Infection Biology ( ID 1145) 7270 Davos Platz Festanstellung 100% Alle Jobs dieses Anbieters  Meinen Arbeitsweg berechnenJETZT BEWERBEN

Postdoctoral Position in Natural Product Research (Pharmaceutical Biology) The Department of Pharmaceutical Sciences of the University of Basel is an Academic Drug Discovery & Development Center, which comprehensively covers academic drug research throughout pre-clinical and clinical research phases. The Pharmaceutical Biology Group (Head Prof. Robin Teufel) within the Department is searching for a postdoctoral researcher with training and experience in natural product research, biosynthesis, protein biochemistry and analytical chemistry. Your position A postdoctoral position is available in the research group of Prof. Robin Teufel that focuses on the isolation of bioactive natural products from microorganisms and plants as well as the elucidation of the underlying biosynthetic pathways. You will be exploring enzymes from plant natural product biosynthesis including their mechanistic and structural investigation as well as possible modification by bioengineering for the production of pharmaceutically useful natural products and lead compounds. The place of work is at the Pharmazentrum in Basel. Fluency in English (C2 level) is required. Your profile We are looking for a candidate with a doctoral degree in a field related to pharmaceutical biology, biochemistry or chemistry. Experience in natural product research is required. Knowledge in natural product analysis (especially mass spectrometry & molecular networking, NMR etc.), enzymology, protein design, structural biology, molecular biology, and/or bioinformatics is furthermore advantageous. As a postdoctoral researcher, you will also supervise master students on occasion. We offer you The candidate will join a dynamic multidisciplinary research group of pharmacists, chemists and biologists working on the isolation/characterization of natural products and the underlying biosynthesis in one of the world's hubs for pharmaceutical research. Enjoy the vibrant scientific community at the University of Basel with great possibilities for internal and external collaborations as well as state-of-the-art instrumentation and infrastructure both in-house and close-by. As part of our team, you will receive supportive mentoring, a generous salary and enjoy the high quality of life in Switzerland for two to a maximum of four years. Application / Contact We are looking forward to receiving your online application with the following documents: brief cover letter, up-to-date curriculum vitae (CV) and contact details of 2 referees. The CV should list relevant experience and/or academic coursework, which can confirm the candidate's training in the methods listed above. Please note that we exclusively accept applications submitted through our online application portal. Applications via email, postal services or agencies will not be considered. For general inquiries please send an email to Write an email https://pharma.unibas.ch/en/persons/robin-teufel/ Universität Basel4000 Basel

Postdoctoral position in the Computational Structural Biology laboratoryPostdoctoral position in the Computational Structural Biology laboratory (Andrea Cavalli) Artificial Intelligences applied to antibody discovery The Computational Structural Biology laboratory (Andrea Cavalli) at the Institute for Researchin Biomedicine (IRB, Bellinzona, Switzerland) is recruiting a highly motivated postdoc to workon the development and application of artificial intelligence (AI), in particular large languagemodels (LLM), to the discovery of antibodies. The project is funded by a Sinergia grant fromthe Swiss National Science Foundation (SNSF) and will be carried out in a laboratory affiliatedto the Swiss Institute of Bioinformatics (SIB). Preferred starting date is beginning of 2024. Qualification: Our international team will welcome candidates with a PhD in Computational Sciences,Computational Biology or related fields, with less than 3 years of postdoctoral experience andexpertise in development and application of novel AI based methods, such as large languagemodels (LLM). Furthermore, candidates should have strong programming skills (Python) andexperience in structural biology. Interested candidates are kindly requested to send an application containing a cover letter (1page), CV (1 page), summary of previous research (1 page), and the contact information oftwo professional references to: [email protected].

About the roleYou will be responsible for providing critical biochemical and cell assay data for multiple biologics drug discovery projects using state-of-the-art technologies. This is a lab-based role involving independent design, execution and interpretation of scientific experiments. Furthermore, you effectively communicate your findings and recommendations as part of a multi-disciplinary project team. Your work provides crucial data about protein activity in cellular assays. You develop and implement these assays by using a diverse set of formats and readouts, ranging from low- to high-throughput. You work in a highly collaborative, team-oriented and fast-paced startup environment with a strong commitment to delivering in ways that cut across traditional industry boundaries.What you'll do…Develop biochemical and cell-based 96- or 384-well functional assays for screening and pharmacologically characterize biologics for drug discovery or technology development projects.Hands-on work in the cell culture lab combined with handling pipetting robots and high-end analytical instruments like plate readers, FACS and imaging systems.Experience with human cell lines, primary and stem cells. As well as isolation of PBMCs handling, sorting, and characterisation.Design, plan and perform cell-culture experiments and assays in the context of cancer, autoimmune/inflammatory diseases and other disease models.  Ensure own work is compliant with General Laboratory Standards, Safety, Health and Environment standards and all other relevant internal Peptone standards and external regulations.Deliver work on time and within the allocated budget.Perform statistical data analysis and interpretation of analysis results.Determine SOPs, reports and presentations.Present and discuss data in team meetings with associated subject matter experts.Transfer methods to CROs and manage these collaborations to ensure scientific quality and timelines.Perform maintenance of high-end laboratory devices and instruments.Comply with industry standards of good research practice principles, including relevant documentation procedures in an ELN system.Actively contribute to multi-disciplinary research drug discovery and technology projects, effectively recommend and contribute to team decisions.Maximize value extraction from every measurement in the lab.What you Bring…Ideally PhD or MSc degree in Immunology with relevant hands-on experience in the lab.Industry experience in a drug discovery environment is a plusExperience and in-depth technical knowledge of biologics assay development, screening and use of automation, with a commitment to quality and scientific rigour.Strong hands-on experience in cell-based assays (e.g., cell culture techniques, viability and phenotypic assays, FACS, image platforms, etc.).Hands-on experience with imaging platforms for live cell analysis and minimal perturbation experiments is a plus.Solid experience in immunological assays using and purifying human PBMC's.Hands-on experience with cell-based, primary and iPSC-derived neuronal models in the context of identification and validation of novel targets is a plus.Ability to solve challenges creatively and a drive to contribute to the development of new and improved assay technologies and processes.Experience in biochemical and molecular biology methods (e.g., ELISA, WB and enzyme assays)Experience in biochemical assays like HTRF, AlphaLISA and AlphaScreen is a big plus.Experience in high throughput technologies and automated liquid handling systems is a plus.Knowledge of statistical data analysis and experimental design (DoE) is of advantage.Strong computer, scientific, and organizational skills with great attention to detail.Proactive, independent, structured and highly motivated approach to work combined with excellent problem-solving skills and a great team spirit.Strong team player with good communication skills and experience of working in multi-disciplinary teams and contributing to collaborations.Fluency in spoken and written English is mandatory. Fluency in Italian is a plus. Demonstrate independent judgment in technique and method selection, protocol and study design and execution, data analysis and use of standard practices and procedures for a variety of problems of moderate scope and complexity to meet assigned objectives.About usPeptone is a category-defining translational biophysics company focusing on the intersection of physics, biology and supercomputing. Currently, we are in the scale-up phase, where our efforts go into building out our experimental lab capacity in Switzerland while growing the HPC and ML teams in the UK. Our interdisciplinary team consists of physicists, biologists, computational chemists, software engineers and mathematicians. We have created a company culture that is based on scientific and personal integrity and a highly supportive, inclusive attitude. Our curiosity and drive stem from the shared passion to contribute to our scientific understanding of proteins and to translate these insights into reality by developing drugs that make people's lives better. Corporate CultureDefault to transparency. As individuals, we view transparency as a lifestyle of authenticity, respect, and honesty. As a team, we view transparency as an effective way to work remotely and establish a culture of trust.Cultivate positivity. We strive to approach things positively while realizing all emotions are valid. We encourage constructive feedback from team members and business partners to foster positive collaborations.Show gratitude. We regularly stop and demonstrate gratitude for our circumstances. We are reverent to our team, investors, advisors, and commercial partners who believed in us from the beginning and will always use this as a guiding light to growth.Practice reflection. We believe the act of introspection is where true learning and life-changing adjustments originate. We approach discussions intentionally and think through all angles.Improve consistently. We are biased toward action and have a higher expectation of ourselves and of our technology than others have of us. We aim to be fully engaged in our work and activities and fully disconnected when we're not working.Act beyond yourself. We consider the bigger picture, knowing our work goes beyond ourselves. We are not afraid of the less-travelled path if it holds to our values and betters the world.Build Sustainably. Sustainability is at the core of our technology, research, and team values. Oppenheimer's supercomputer runs on 100% renewable energy and mitigates the need for traditional high-throughput experiments in our Swiss lab. Our team is incentivized and committed to growing a sustainable future and corporate culture.Diversify. Diversity at all levels is paramount in translating biophysics to first-in-class medicines while embracing the serendipity of science. Diversity in mindsets, gender, skills, backgrounds, and — because we are geeks,  protein sequences — are key to building an impactful future for our patients.Patient Passion. Our team is interwoven with a passion for understanding the “why” of protein drug failures to avoid them. The integration of the Oppenheimer platform with our Swiss pre-clinical laboratory is an unwavering commitment to developing first-in-class protein therapeutics for our patients.Reverence to the giants. We embrace the fortitude and ingenuity of all the great minds and teams who advanced the field of protein biophysics to enable cutting-edge therapeutics. It is our honour to collaborate in this arena to pay homage to scientists who laid the very foundation. Committed to our Corporate Culture to embrace diversity, Peptone Ltd and its affiliates are Equal Opportunity and Affirmative Action employers building a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; colour; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Our MissionDelivering first-in-class medicines for better patient outcomes is our obsession. Translating the biophysics of intrinsic protein disorder to generate de novo protein therapeutics is our passion.What we bring…A non-hierarchical environment where everyone has a voice to influence and shape the company's future directionAn appreciative atmosphere with fair salaries, company benefits and top-class working equipmentA highly dynamic environment with plenty of opportunities for career development A highly skilled and interdisciplinary team that is passionate about proteins, science and businessA unique company allowing you to push the boundaries of biopharmaceutical drug development A fast-paced company with novel science and academic rigour at its core A company that values your contribution to scientific endeavour and supports the presentation and publication of your novel discoveries A flexible working setup to ensure a work-life balance Über das Unternehmen:Peptone

Spatial Biology Matrix LeadThe Position In Roche’s Pharmaceutical Research and Early Development organization (pRED ), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed. 360 Labs Initiative at a Glance The 360 Labs are a new capability that is currently being built up within the Pharmaceutical Research and Early Development organization (pRED ). The primary mission of this effort is to provide greater access and support for the use of cutting-edge biomedical research technologies by scientists across our discovery portfolio. Operating as an integrated ecosystem, the 360 Lab environment will deliver core scientific technologies, expertise and enabling activities, as well as facilitate knowledge sharing and learning experiences in close collaboration with our therapeutic areas and functions. Together, these efforts will serve to increase the speed, enhance the robustness and improve the sustainability of our exploratory research and early discovery activities. We are currently recruiting scientific professionals with varied backgrounds in Flow Cytometry, Genomics, Proteomics, Histopathology and Microscopy / Imaging. In these new roles, your collaborative mindset is as valued as your scientific expertise. The 360 Labs are by nature a hands-on, interactive workplace where face to face presence in our labs is a priority. Our ambition is to bring to life a thriving workplace environment, acting as an highly integrated ecosystem, supporting research and development, working collaboratively, and focused on fostering excellence and sustainability. Job Mission and Impact The 360 Labs Initiative is seeking a Matrix Leader for Spatial Biology. You will have a strong background in the development and application of spatial approaches (both genomics and imaging-based) to understand disease biology. You will operate as a part of a matrix team and will collaborate closely with the platform heads, lab scientists and data analysts from each of the 360 Labs technology platforms, as well as with experts from our therapeutic disease areas and functions to conceptualize and execute our spatial biology strategy to support discovery projects undertaken within the 360 Labs technology ecosystem. Your Role and Responsibilities Act as a strategic visionary, providing key guidance and oversight in the deployment and application of spatial biology approaches across the discovery research space in pRED. Serve as a key member of the 360 Labs leadership team, working closely with the Global Head, to develop a bold vision and strategy for spatial biology by close interaction with senior leaders and key stakeholders across pRED. Serve as a Matrix Leader collaborating across the 360 Labs technology ecosystem along with scientific experts from our therapeutic areas and functions to prioritize and implement innovative spatial biology strategies to enable the exploration of disease-relevant hypotheses. Work collaboratively to continually evolve our spatial biology strategy by innovating new approaches, staying up to date with the scientific literature, actively engaging with internal and external spatial biology communities, and continuously evaluating new technologies in the spatial biology space. Your Profile Required Proven track record of engagement with senior leaders and key stakeholders and leading cross-functional teams. A PhD degree in biology, chemistry, or a related field with 5 yrs professional experience in an academic setting and / or pharmaceutical industry / biotech sector. An experienced experimentalist with in-depth theoretical and hands-on knowledge in the development and application of genomics and imaging-based spatial biology assays to understand how cells organize and interact across complex tissue landscapes. Established track record of scientific accomplishments and successful collaborations documented via publications in high-impact scientific journals and presentations at international conferences. Familiarity with the bioinformatics tools and programming languages commonly used in the analyses and interpretation of spatial biology-related datasets. Strong awareness of the emerging trends and technology developments across the spatial biology space. In addition to your scientific expertise and critical technical skills we are looking for candidates who: are a strategic leader that can architect a compelling vision; serve as a coach to develop and mentor junior and senior team members; and act as a catalyst by leading by example; are curious, have a growth mindset, are resourceful and flexible in problem solving, have excellent organizational skills, can think outside the box, and have a demonstrated ability to implement new ideas in a fast-paced research environment; bring excellent written communication and presentations skills with a high fluency in English; have a keen interest in continuously building a personal network and who will thrive in a dynamic, inclusive environment which gives you full accountability for your own contributions and development; have an excellent understanding of the operations processes involved in early drug discovery & development. Your Location This position is based in Basel. Our commitment Roche commits to recognizing talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career. We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be. Who we are At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity. Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more. Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events. We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche. Roche is an Equal Opportunity Employer.