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Pre-Clinical Project Manager
Haya Therapeutics SA, Epalinges, Switzerland
Pre-Clinical Project ManagerLocation:Lausanne, SwitzerlandRequests a full time presence on-site Conditions of Employment: Proof of Eligibility to work in Switzerland (Swiss work permit or Swiss / European citizenship or graduated within the last 6 months from a Swiss academic institution) So, if you think you are a strong fit for this position, please apply today! Please send your CV and Cover Letter to [email protected] . Please specify the position you are applying for and use the “PC-PM” identifier in your cover letter and email subject line. The position comes with an excellent compensation and benefits package. Apply for this position About the job We are seeking highly motivated candidates to join our Pre-clinical and translational development team in Lausanne and contribute to pre-clinical drug development across different programs. In this role you will be directly reporting to senior company leadership. You will be joining a highly dynamic scientific team and will focus on generating and experimentally executing actionable pioneering hypotheses to drive novel platform and therapeutic applications. HAYA seeks candidates who are creative, scientifically bold, independent, goal-oriented, excellent communicators, motivated to learn new skills and work collaboratively in a fast-paced entrepreneurial environment. Primary responsibilities Organizing, overseeing and managing non-clinical studies with Contract Research Organizations (research and GLP) to support the product development Driving preclinical projects and projects related activities: applying project management skills in planning, initiating, risk assessing, executing and tracking of project activities, timelines and budget Presentation of pre-clinical development activities to company leadership and stakeholders Accurately writing preclinical protocols, study reports to support interaction with authorities and regulators Primary point of contact for communication for internal and external collaborators regarding pre-clinical in vivo studies Preparation of and participating in internal and external scientific meetings and communications Actively maintaining a preclinical databases related to samples and materials Ensure adherence to regulatory guidelines in the context of preclinical studies Requirements The ideal candidate for this position needs: Master or Ph.D. in pharmacology, biochemistry, molecular biology (or equivalent). At least 2 years of project management experience in a drug development or pre-clinical study management setting in industry Excellent verbal and written communication skills in English. Very good time management skills and ability to multi-task and prioritize work under pressure Excellent organizational skills and attention to detail Experience with nucleic acid therapeutics (e.g. antisense or siRNAs) is a plus. Knowledge of the drug development process and implications related to disciplines like pharmacology, ADME, formulation, drug safety, histopathology and IP. Background and knowledge of fibrotic diseases and experience fibrotic disease models is a plus (e.g. kidney fibrosis, lung fibrosis, cancer associated fibroblasts) Proficiency with NGS technologies and data-sets. Core Values Creativity & Innovation. Scientifically curious and bold. Generates new and creative approaches to problem solving. Positive ‘can-do’ attitude. Views the toughest challenges as the greatest opportunities for personal growth and company innovation. Able to challenge convictions and dogma. Teamwork . Fully engaged in facilitating personal and team success. Reaches out to peers and cooperates with the team to establish an overall collaborative work environment. Often solicits and responds well to constructive feedback. Possesses good written and oral communication skills with the ability to clearly and concisely convey ideas and opinions. Flexibility/adaptability. Adjusts quickly to changing strategic and tactical priorities. Comfortable with ambiguity. Self-starter mentality. Fast-acting/efficient. Proactive and quick decision making with a strong work ethic to produce high-quality results while fostering a positive work environment. Focuses on key tasks and priorities. Demonstrates tenacity and willingness to go the distance to get something done. Integrity. Does not cut corners. Does what is right not just what is politically expedient. Speaks plainly and truthfully. Earns trust and maintains confidences. Expects a high level of personal performance and team performance. Follows-through on commitments. Critical thinking. Learns quickly. Demonstrates ability to proficiently understand new information and to independently pursue and achieve meaningful outcomes. Able to structure and process qualitative/quantitative data and draw key conclusions. About Us HAYA Therapeutics is a precision medicines company developing RNA-guided programmable therapeutics targeting the regulatory genome for serious health conditions including cardiovascular disease and cancer. The company is using its innovative cell-state modifying platform to gain novel insights into the biology of long non-coding RNAs (lncRNAs), - the ‘dark genomes’ information processing features and ‘source code’. HAYA’s lead therapeutic candidate is HTX-001, an antisense oligonucleotide targeting Wisper, which is a tissue and cell-specific cardiac lncRNA known to play a role in heart failure. The company is also developing a pipeline of lncRNA-targeting candidates for the cell-specific treatment of diseases in other tissues, including the lungs and the microenvironment of solid tumor cancers. Headquartered at the life sciences park Biopôle in Lausanne, Switzerland with laboratory facilities at JLABS @ San Diego, HAYA is led by a world-class team of experts in programmable and precision RNA-targeted therapeutics and is supported by a strong investor consortium. HAYA’s mission is to identify and develop breakthrough disease-modifying therapeutics with the potential for greater efficacy, safety, and accessibility than existing treatments.
Senior Genomic Biomarker Scientist
Haya Therapeutics SA, Epalinges, Switzerland
Senior Genomic Biomarker ScientistLocation:Lausanne, SwitzerlandRequests a full time presence on-site Conditions of Employment: Proof of Eligibility to work in Switzerland (Swiss work permit or Swiss / European citizenship) So, if you think you are a strong fit for this position, please apply today!Please send your CV and Cover Letter to [email protected]. Please specify the position you are applying for. Excellent salary and benefits package offered. Apply for this position About the job We are seeking highly motivated candidates to join our R&D team in Lausanne and contribute to the development and application of advanced technologies in RNA-based therapeutics and diagnostics. HAYA seeks candidates who are creative, scientifically bold, independent, goal-oriented, excellent communicators, motivated to learn new skills and work collaboratively in a fast-paced entrepreneurial environment. Senior Genomic Biomarker Scientist As an experienced and engaged Senior Genomic Biomarker Scientist, you will work in close collaboration with computational biology and pre-clinical R&D teams. You will apply your scientific acumen and creativity to build ViewHAYATM, a top-notch platform for biomarker discovery and validation. You will drive this platform forward to identify and develop CDx for HAYA’s therapeutic assets. You will provide matrix leadership and inspire others with your creative ideas as well as your technological and domain insights. Responsibilities will include, but are not limited to, the following: Build and lead a small team of ~2-3 scientists to drive novel diagnostic and prognostic RNA biomarker discovery studies. Design, conceptualize and develop experimental and analytical procedures. Lead the strategy, development, validation and implementation of genetics and genomics-based biomarker assays. Be a subject expert in order to evaluate and apply genetics and genomics technologies and assays to ensure we gain relevant insights from precious sample materials. Manage all aspects of out-sourced (CROs) work packages. Actively participate in internal and external scientific meetings through presentations and critical evaluation of both internal results and emerging scientific literature. Inspire your team members and other scientists and train them in the application of new technologies. Qualifications: PhD in molecular and/or RNA biology or related discipline with at least 5 years of experience in biomarker research. Strong expertise in genetics and genomics biomarker assays development. Deep technical expertise in molecular biology (PCR technologies) and next generation sequencing applications across platforms in various matrices (e.g. tissue, blood, body fluids, cells). Strong knowledge with tools, and resources used for the analysis and interpretation of genomic data. Proven excellence in building and managing scientific teams and completing challenging projects. Excellent organization skills and familiarity with a fast-paced work environment. Collaborative spirit and ability to thrive in a matrixed environment. Proven track record of handling multiple high priority tasks in parallel with internal and external collaborators. Excellent written and verbal communication skills. Core Values: Creativity & Innovation. Scientifically curious and bold. Generates new and creative approaches to problem solving. Positive ‘can-do’ attitude. Views the toughest challenges as the greatest opportunities for personal growth and company innovation. Able to challenge convictions and dogma. Teamwork. Fully engaged in facilitating personal and team success. Reaches out to peers and cooperates with the team to establish an overall collaborative work environment. Often solicits and responds well to constructive feedback. Possesses good written and oral communication skills with the ability to clearly and concisely convey ideas and opinions. Flexibility/adaptability. Adjusts quickly to changing strategic and tactical priorities. Comfortable with ambiguity. Self-starter mentality. Fast-acting/efficient. Proactive and quick decision making with a strong work ethic to produce high-quality results while fostering a positive work environment. Focuses on key tasks and priorities. Demonstrates tenacity and willingness to go the distance to get something done. Integrity. Does not cut corners. Does what is right not just what is politically expedient. Speaks plainly and truthfully. Earns trust and maintains confidences. Expects a high level of personal performance and team performance. Follows-through on commitments. Critical thinking. Learns quickly. Demonstrates ability to proficiently understand new information and to independently pursue and achieve meaningful outcomes. Able to structure and process qualitative/quantitative data and draw key conclusions. About Us HAYA Therapeutics is a precision medicines company developing RNA-guided programmable therapeutics targeting the regulatory genome for serious health conditions including cardiovascular disease and cancer. The company is using its innovative cell-state modifying platform to gain novel insights into the biology of long non-coding RNAs (lncRNAs), - the ‘dark genomes’ information processing features and ‘source code’. HAYA’s lead therapeutic candidate is HTX-001, an antisense oligonucleotide targeting Wisper, which is a tissue and cell-specific cardiac lncRNA known to play a role in heart failure. The company is also developing a pipeline of lncRNA-targeting candidates for the cell-specific treatment of diseases in other tissues, including the lungs and the microenvironment of solid tumor cancers. Headquartered at the life sciences park Biopôle in Lausanne, Switzerland with laboratory facilities at JLABS @ San Diego, HAYA is led by a world-class team of experts in programmable and precision RNA-targeted therapeutics and is supported by a strong investor consortium. HAYA’s mission is to identify and develop breakthrough disease-modifying therapeutics with the potential for greater efficacy, safety, and accessibility than existing treatments.
Lab and Operation Manager
Haya Therapeutics SA, Epalinges, Switzerland
Lab and Operation ManagerLocation:Lausanne, SwitzerlandRequests a full time presence on-site Conditions of Employment: Proof of Eligibility to work in Switzerland (Swiss work permit or Swiss / European citizenship) So, if you think you are a strong fit for this position, please apply today! Please specify the position you are applying for and use the “LAB-MNGT” identifier in your cover letter and email subject line. The position comes with an excellent compensation and benefits package. Apply for this position About the job We are seeking highly motivated candidates to join our headquarters in Lausanne. You will be joining a dynamic start-up to improve and implement operations and logistics according to the incoming needs. You will help with enrollments of new employees and be implicated on some financial and high technological projects such as the implementation of the ERP. HAYA seeks candidates who are creative, goal-oriented, excellent communicators, motivated to learn new skills and work collaboratively in a fast-paced entrepreneurial environment. Primary responsibilities Responsible for general lab management and operations Getting in contact with specific manufacturers and suppliers for products availability, turnaround time for production and estimation of delivery Responsible for ordering and invoicing processes Maintenance of the supply chain Coordination of national and international logistics Handling urgent laboratory needs providing in a timely manner solutions and/or alternatives Instrument set-up, maintenance, revision and troubleshooting Provide to leadership and executives record of information Acting as biosafety officer Preparation, revision and implementation of lab related SOPs Support with ERP implementation for lab related processes Electronic reporting systems set-up, maintenance and implementation (ELN, Lims, Benchling, Databases) Requirements The ideal candidate for this position needs: At least a master's degree in science/biology or related field 5 years of professional experience in a similar position sociable, customer-oriented and a team player English as a professional language Ability to lead, motivate and develop a small group Analytical and systematic thinking skills as well as organizational skills resilient and persistent Knowledge of cell culture and molecular biology protocols and workflows Core Values: Creativity & Innovation. Scientifically curious and bold. Generates new and creative approaches to problem solving. Positive ‘can-do’ attitude. Views the toughest challenges as the greatest opportunities for personal growth and company innovation. Able to challenge convictions and dogma. Teamwork. Fully engaged in facilitating personal and team success. Reaches out to peers and cooperates with the team to establish an overall collaborative work environment. Often solicits and responds well to constructive feedback. Possesses good written and oral communication skills with the ability to clearly and concisely convey ideas and opinions. Flexibility/adaptability. Adjusts quickly to changing strategic and tactical priorities. Comfortable with ambiguity. Self-starter mentality. Fast-acting/efficient. Proactive and quick decision making with a strong work ethic to produce high-quality results while fostering a positive work environment. Focuses on key tasks and priorities. Demonstrates tenacity and willingness to go the distance to get something done. Integrity. Does not cut corners. Does what is right not just what is politically expedient. Speaks plainly and truthfully. Earns trust and maintains confidences. Expects a high level of personal performance and team performance. Follows-through on commitments. Critical thinking. Learns quickly. Demonstrates ability to proficiently understand new information and to independently pursue and achieve meaningful outcomes. Able to structure and process qualitative/quantitative data and draw key conclusions. About Us HAYA Therapeutics is a precision medicines company developing RNA-guided programmable therapeutics targeting the regulatory genome for serious health conditions including cardiovascular disease and cancer. The company is using its innovative cell-state modifying platform to gain novel insights into the biology of long non-coding RNAs (lncRNAs), - the ‘dark genomes’ information processing features and ‘source code’. HAYA’s lead therapeutic candidate is HTX-001, an antisense oligonucleotide targeting Wisper, which is a tissue and cell-specific cardiac lncRNA known to play a role in heart failure. The company is also developing a pipeline of lncRNA-targeting candidates for the cell-specific treatment of diseases in other tissues, including the lungs and the microenvironment of solid tumor cancers. Headquartered at the life sciences park Biopôle in Lausanne, Switzerland with laboratory facilities at JLABS @ San Diego, HAYA is led by a world-class team of experts in programmable and precision RNA-targeted therapeutics and is supported by a strong investor consortium. HAYA’s mission is to identify and develop breakthrough disease-modifying therapeutics with the potential for greater efficacy, safety, and accessibility than existing treatments.
1_ZEICHNER(IN) in Epalinges
Flexdental Services SA, Epalinges
Ihre Aufgaben:- Als Zeichner/in erwarten Sie spannende Aufgaben aus den komplexen Bereichen der Neuprojektierung.- Sie studieren die Projekte direkt mit dem Endkunden.- Sie erstellen ein Lastenheft.- Sie zeichnen die Baupläne.- Sie arbeiten zusammen mit dem Projektmanager.- Sie festigen die Beziehung zwischen unserem Unternehmen und unseren Kunden.Sie sind:- Technische/r Zeichner/in mit Spezialisierung auf AutoCAD mit einem EFZ oder einer gleichwertigen Ausbildung.- Der Französischen Sprache mächtig.Die Pluspunkte:- Sie beherrschen die englische Sprache.- Sie sind zwischen 1985 und 2000 geboren.- Sie wohnen in einem Umkreis von 30 km von Lausanne oder Sie beabsichtigen hierhin umzuziehen.Das Arbeitsumfeld:- Das Menschliche steht im Mittelpunkt unserer Werte.- Neue, helle und angenehme Räumlichkeiten mit einfachem Zugang.- Die Arbeit findet immer im Team mit unseren Fachtechnikern statt.- Reisen zu den Standorten sind vorzusehen.- Die Ausbildung zu den zahlreichen Produkten unseres Sortiments ist permanent und progressiv.ZEICHNER(IN) FÜR DIE PROJEKTPLANUNG «ZAHNARZTPRAXIS»
2_TECHNIKER(INNEN) IM in Epalinges
Flexdental Services SA, Epalinges
Ihre Aufgaben:- Sie sind für die Wartung von zahnmedizinischen Geräten zuständig.- Sie festigen die Beziehung zwischen unserem Unternehmen und unseren Kunden.- Sie führen die Installationen der Geräte aus unserem Sortiment durch (wenn nötig im Zweierteam).- Sie leisten technischen Support über Fernwartung.Sie verfügen über:- Eine technische Bildung mit einer Ausbildung des Typen EFZ, FH, ETH oder gleichwertig.- Einen Werdegang der Sie aufgrund Ihrer Erfahrung, befähigt diese Funktion zu übernehmen.- Eine signifikante Erfahrung in unserem Bereich.- Die Beherrschung der französischen Sprache, um die Fachliteratur zu verstehen.Die Pluspunkte:- Sie beherrschen die englische Sprache.- Sie sind zwischen 1985 und 2000 geboren.- Sie wohnen in einem Umkreis von 30 km von Lausanne oder Sie beabsichtigen hierhin umzuziehen.Das Arbeitsumfeld :- Das Menschliche steht im Mittelpunkt unserer Werte.- Neue, helle und angenehme Räumlichkeiten mit einfachem Zugang.- Die Arbeit findet im Team mit viel Austausch statt.- Die Reisen sind zahlreich, aber immer in Kontakt mit unserer Zentrale.- Die Ausbildung zu den zahlreichen Produkten unseres Sortiments ist permanent und progressiv.AUSSENDIENST 2 TECHNIKER(INNEN) IM AUSSENDIENST FÜR DIE SCHWEIZ – ZAHNMEDIZINISCHER BEREICH